The Apoproteins as Genetic Markers for Familial Hypertriglyceridaemia

1.  Introduction

Plasma lipids play a role in the aetiology of coronary heart disease. Evidence now concludes that there is a definite correlation between raised plasma lipid levels and the onset of ischaemic heart disease, and that appropriate therapeutic intervention lowers this risk. Therefore the apoproteins may serve as better, even more useful, indicators of the existence of familial hyperlipidaemia (Avogaro, 1979). Especially because the determination of plasma apolipoproteins may enable earlier diagnosis to be made – hopefully among younger age groups than is presently possible. or example (in 1984) Type IV familial hypertriglyceridaemia at present defies pre-adulthood detection by current methods.

2.  The apolipoproteins – a review


To be continued.

March, 1984.


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